Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955328 | 0.85 | CA1 (0.44) | CA1CA2NFE2L2MAPTKDM4E | |
| SCHEMBL16953029 | 0.84 | CA1 (0.40) | CA1CA2NFE2L2MAPTKDM4E | |
| SCHEMBL16957325 | 0.82 | NPC1 (0.35) | MAPTALDH1A1PDCD1CD274 | |
| SCHEMBL16960025 | 0.82 | CA1 (0.39) | CA1CA2NFE2L2CA12 | |
| SCHEMBL129790 | 0.82 | ALDH1A1 (0.46) | CA1CA2MAPTKDM4EALDH1A1 | |
| SCHEMBL16952390 | 0.75 | CA1 (0.69) | CA1CA2NFE2L2MAPTKDM4E | |
| SCHEMBL95873 | 0.75 | ALDH1A1 (0.53) | CA1CA2KDM4EALDH1A1MAPK1 | |
| SCHEMBL1836066 | 0.75 | CA1 (0.48) | CA1CA2MAPTKDM4EALDH1A1 | |
| SCHEMBL16955330 | 0.75 | GABRA1 (0.46) | CA1CA2MAPTKDM4EALDH1A1 | |
| SCHEMBL10946385 | 0.75 | PDCD1 (0.46) | MAPTKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |