Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955330 | 0.91 | GABRA1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL129805 | 0.89 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL12683752 | 0.88 | ALOX5 (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL4897798 | 0.87 | PDCD1 (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL95873 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EMAPK1CA2 | |
| SCHEMBL1836066 | 0.87 | CA1 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL10946385 | 0.87 | PDCD1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL1679589 | 0.85 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL3328387 | 0.85 | KMT2A (0.40) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL560783 | 0.85 | MEN1 (0.43) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1879562-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | Imperial Innovations Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006097744-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | IMPERIAL INNOVATIONS LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
| EP-0735425-B1 | Esterification product of aromatic novolak resin with quinone diazide sulfonyl compound | SHIPLEY CO LLC (US) | 2003-06-04 | — | — | EP | disclosed |
| US-5589553-A | PHOTORESISTS | SHIPLEY COMPANY, L.L.C. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0735425-A2 | Esterification product of aromatic novolak resin with quinone diazide sulfonyl compound | Shipley Company LLC (US) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | ALDH1A1 3341/4885SMN1; SMN2 3496/4885KDM4E 2572/4885 |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | ALDH1A1 2930/4885SMN1; SMN2 3296/4885KDM4E 2001/4885 |
| US-20090221702-A1 | COMPOUNDS | NCEH1, NME2, HRH3 | ALDH1A1 3748/4885SMN1; SMN2 3298/4885KDM4E 2343/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | ALDH1A1 3376/4885SMN1; SMN2 3143/4885KDM4E 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.