Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | BRD2 | P25440 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959385 | 0.87 | PLA2G2A (0.39) | ALDH1A1HTTRXRARARGPPARG | |
| SCHEMBL16952802 | 0.87 | LMNA (0.33) | ACACBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16955026 | 0.85 | KMT2A (0.41) | BRD4BRD2CREBBPPTGS2MAPT | |
| SCHEMBL16961351 | 0.83 | PDE4A (0.33) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16954575 | 0.82 | PTGS2 (0.39) | ACACBBRD4BRD2CREBBPPTGS2 | |
| SCHEMBL16956238 | 0.82 | MEN1 (0.35) | ACACBBRD4BRD2CREBBPPTGS2 | |
| SCHEMBL16956111 | 0.80 | GABRA1 (0.33) | KDM4E | |
| SCHEMBL16955778 | 0.80 | MAOB (0.35) | BRD4BRD2CREBBPMAPTALDH1A1 | |
| SCHEMBL16959315 | 0.80 | ESR1 (0.45) | BRD4BRD2CREBBPALDH1A1MEN1 | |
| SCHEMBL16961574 | 0.80 | KAT6A (0.40) | BRD4BRD2CREBBPALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |