Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951879 | 0.82 | P2RX7 (0.38) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16957551 | 0.82 | TAS1R3 (0.38) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16960098 | 0.82 | ALDH1A1 (0.38) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16951918 | 0.82 | TSHR (0.48) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16952007 | 0.82 | CYP11B1 (0.38) | P2RX7ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL16952726 | 0.82 | TRPA1 (0.43) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL16953269 | 0.81 | P2RX7 (0.37) | P2RX7TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL16951096 | 0.81 | TSHR (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16953858 | 0.80 | KAT6A (0.40) | P2RX7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16952565 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |