Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950503 | 0.86 | L3MBTL1 (0.40) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL16957325 | 0.85 | NPC1 (0.35) | NPC1RAB9ATP53CYP4F2CYP4A11 | |
| SCHEMBL16960631 | 0.84 | NQO1 (0.37) | NPC1TP53ALDH1A1TLR4L3MBTL1 | |
| SCHEMBL16953875 | 0.83 | ELANE (0.37) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL16953029 | 0.83 | CA1 (0.40) | ALDH1A1SMN1; SMN2GAAKDM4EHPGD | |
| SCHEMBL16957328 | 0.82 | CYP4F2 (0.42) | NPC1RAB9ATP53CYP4F2CYP4A11 | |
| SCHEMBL8344768 | 0.80 | PTGER4 (0.35) | NPC1RAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL16956193 | 0.79 | TLR4 (0.35) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL16959774 | 0.79 | CA1 (0.43) | NPC1RAB9AALDH1A1GAATLR4 | |
| SCHEMBL218773 | 0.77 | GSK3A (0.42) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |