Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960631 | 0.87 | NQO1 (0.37) | L3MBTL1GSK3AELANEALDH1A1NPC1 | |
| SCHEMBL16953875 | 0.86 | ELANE (0.37) | L3MBTL1MAPTNPSR1GSK3AELANE | |
| SCHEMBL16956195 | 0.86 | PDXK (0.35) | L3MBTL1MAPTNPSR1GSK3AALDH1A1 | |
| SCHEMBL27754527 | 0.84 | CA1 (0.44) | L3MBTL1MAPTNPSR1GABRA1GABRB2 | |
| SCHEMBL14999526 | 0.84 | CA1 (0.41) | L3MBTL1MAPTGABRA1GABRB2ALDH1A1 | |
| SCHEMBL16950925 | 0.82 | GABRA1 (0.41) | L3MBTL1MAPTNPSR1GABRA1GABRB2 | |
| SCHEMBL218773 | 0.80 | GSK3A (0.42) | L3MBTL1MAPTNPSR1GSK3AALDH1A1 | |
| SCHEMBL16956478 | 0.80 | SCN4A (0.38) | MAPTGSK3AALDH1A1KDM4EHPGD | |
| SCHEMBL7131498 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL16958358 | 0.79 | ALDH1A1 (0.48) | L3MBTL1MAPTGSK3AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |