Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956985 | 0.84 | ALDH1A1 (0.38) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL16959250 | 0.81 | HSD17B10 (0.51) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL16954542 | 0.81 | PTPRC (0.39) | LMNATSHRALDH1A1GPR35TP53 | |
| SCHEMBL16957705 | 0.81 | ALDH1A1 (0.51) | LMNAHTTKMT2ATSHRALDH1A1 | |
| SCHEMBL16961858 | 0.81 | ALDH1A1 (0.49) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL16958012 | 0.81 | LMNA (0.42) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL16955468 | 0.80 | CYP1A2 (0.41) | MEN1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL16955947 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2ATSHRALDH1A1GPR35 | |
| SCHEMBL16957422 | 0.79 | TSHR (0.43) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL16955994 | 0.78 | VCAM1 (0.48) | LMNAMEN1HTTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |