Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960641 | 0.83 | L3MBTL1 (0.39) | MAPTL3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL16958312 | 0.83 | L3MBTL1 (0.41) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL16959581 | 0.82 | GAA (0.47) | MAPTL3MBTL1POLBALDH1A1ATM | |
| SCHEMBL16953417 | 0.82 | TSHR (0.44) | MAPTL3MBTL1RAB9AALDH1A1HPGD | |
| SCHEMBL16956296 | 0.81 | MAPT (0.44) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL16954699 | 0.78 | TRPV4 (0.46) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16950474 | 0.78 | MAPT (0.45) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL9945918 | 0.77 | L3MBTL1 (0.46) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL16956517 | 0.76 | MAPT (0.48) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL16952366 | 0.76 | MAPT (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |