Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962727 | 0.85 | LTA4H (0.38) | TSHRLTA4HCYP3A4 | |
| SCHEMBL16952746 | 0.85 | RXRA (0.44) | NQO1TSHRTDP1MAPTLMNA | |
| SCHEMBL16955449 | 0.83 | NQO1 (0.50) | NQO1TSHRTDP1LTA4HMAPT | |
| SCHEMBL16954511 | 0.82 | HMGCR (0.32) | TSHRMAPTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL25468623 | 0.81 | NQO1 (0.46) | NQO1EPHX2NR1H4TSHRTDP1 | |
| SCHEMBL278323 | 0.81 | NQO1 (0.46) | NQO1EPHX2NR1H4TSHRTDP1 | |
| SCHEMBL16958874 | 0.80 | CA1 (0.38) | TDP1MAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL16961142 | 0.79 | GABRA1 (0.30) | — | |
| SCHEMBL16951572 | 0.77 | NQO1 (0.43) | NQO1TSHRTDP1LTA4H | |
| SCHEMBL16954496 | 0.77 | ESR1 (0.50) | NQO1TSHRTDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |