Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SOD1 | P00441 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955550 | 0.86 | FAAH (0.42) | L3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL16957166 | 0.85 | NQO1 (0.39) | RXRARXRBRXRGL3MBTL1MAPT | |
| SCHEMBL16952665 | 0.83 | SCN9A (0.42) | RXRARXRBRXRGMAPTSOD1 | |
| SCHEMBL16955449 | 0.82 | NQO1 (0.50) | MAPTNQO1ALDH1A1TSHRTDP1 | |
| SCHEMBL12128793 | 0.82 | RXRA (0.53) | RXRARXRBRXRGL3MBTL1MAPT | |
| SCHEMBL16957340 | 0.81 | GRM5 (0.40) | RXRARXRBRXRGL3MBTL1MAPT | |
| SCHEMBL16961413 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MAPTLMNAATMMAPK1 | |
| SCHEMBL16953945 | 0.77 | NQO1 (0.41) | L3MBTL1MAPTNQO1ALDH1A1GAA | |
| SCHEMBL16952298 | 0.77 | RXRA (0.47) | RXRARXRBRXRGL3MBTL1MAPT | |
| SCHEMBL16958401 | 0.75 | CES2 (0.41) | RXRARXRBRXRGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |