Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960900 | 0.82 | TRPA1 (0.38) | MAPTTRPA1LMNAKMT2ACYP1A2 | |
| SCHEMBL16952366 | 0.82 | MAPT (0.33) | SRCMAPTRXFP1NR3C1PGR | |
| SCHEMBL16956297 | 0.81 | L3MBTL1 (0.33) | MAPTRXFP1LMNACYP1A2CYP2C9 | |
| SCHEMBL16955596 | 0.81 | PSEN1 (0.37) | MAPTTRPA1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16958607 | 0.81 | PSEN1 (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL16953099 | 0.79 | TRPA1 (0.35) | SRCMAPTRXFP1TRPA1LMNA | |
| SCHEMBL16961562 | 0.78 | NQO1 (0.41) | MAPTLMNAKMT2ACYP1A2MEN1 | |
| SCHEMBL16951208 | 0.78 | ADRA2A (0.41) | ADRA1AHSD17B10 | |
| SCHEMBL16957264 | 0.77 | PDE2A (0.42) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16958073 | 0.77 | CYP2A6 (0.38) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |