Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 13/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 13/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 13/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 13/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 13/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 13/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955215 | 0.83 | MAPK1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16960900 | 0.81 | TRPA1 (0.38) | LMNAMAPK1NLRP1SMN1; SMN2 | |
| SCHEMBL16958130 | 0.81 | SRC (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL16951787 | 0.80 | LMNA (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16955596 | 0.79 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16956297 | 0.79 | L3MBTL1 (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL16960528 | 0.79 | CYP3A4 (0.39) | LMNAMAPK1 | |
| SCHEMBL16954723 | 0.78 | ALDH1A1 (0.40) | LMNAMAPK1 | |
| SCHEMBL16953064 | 0.77 | GABRA1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16958927 | 0.77 | GAA (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |