Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962011 | 0.84 | ALDH1A1 (0.33) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16956756 | 0.83 | LMNA (0.33) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16951697 | 0.82 | KMT2A (0.38) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16962238 | 0.81 | KMT2A (0.49) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16959741 | 0.80 | KMT2A (0.35) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16961294 | 0.79 | NOTUM (0.40) | KMT2ARAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL16952000 | 0.78 | TSHR (0.31) | KMT2APOLBSMN1; SMN2 | |
| SCHEMBL16952462 | 0.78 | CES2 (0.32) | KMT2A | |
| SCHEMBL16961344 | 0.78 | GABRA1 (0.38) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL16950923 | 0.76 | CA1 (0.36) | KMT2APOLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |