Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959581 | 0.85 | GAA (0.47) | MEN1KMT2AALDH1A1L3MBTL1SLC6A2 | |
| SCHEMBL16959649 | 0.83 | MEN1 (0.43) | MEN1KMT2ATTRLMNAALDH1A1 | |
| SCHEMBL16958642 | 0.81 | MAPT (0.43) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL16959823 | 0.81 | KDM4E (0.39) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL16961775 | 0.81 | ADRA1A (0.54) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16950337 | 0.80 | KDM4E (0.38) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL16951333 | 0.79 | LPAR1 (0.41) | MEN1KMT2ATTRLMNAALDH1A1 | |
| SCHEMBL16958889 | 0.77 | CYP3A4 (0.39) | MEN1KMT2ALMNAALDH1A1SLC6A4 | |
| SCHEMBL16960169 | 0.77 | TP53 (0.39) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL16952763 | 0.77 | PPARG (0.33) | LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |