Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960641 | 0.85 | L3MBTL1 (0.39) | KDM4ESLC6A2SLC6A4CYP2D6ALDH1A1 | |
| SCHEMBL16953760 | 0.85 | ADRA2A (0.38) | KDM4EHTR2AHTR2CNFE2L2SMN1; SMN2 | |
| SCHEMBL16961775 | 0.83 | ADRA1A (0.54) | HTR2AADRA2AADRA1ACYP2D6MEN1 | |
| SCHEMBL16950337 | 0.81 | KDM4E (0.38) | KDM4ESMN1; SMN2USP2ADRA2AADRA1A | |
| SCHEMBL16958455 | 0.81 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL16957922 | 0.81 | HTR2C (0.42) | KDM4EHTR2AHTR2CUSP2HTR2B | |
| SCHEMBL16952708 | 0.80 | NFE2L2 (0.41) | KDM4EHTR2AHTR2CNFE2L2ADRA2A | |
| SCHEMBL16957375 | 0.79 | L3MBTL1 (0.37) | KDM4EHTR2AHTR2CSMN1; SMN2SLC6A2 | |
| SCHEMBL16951751 | 0.77 | NFE2L2 (0.42) | KDM4EHTR2AHTR2CNFE2L2SMN1; SMN2 | |
| SCHEMBL16960469 | 0.77 | POLB (0.32) | PTGS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |