Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959631 | 0.87 | FFAR4 (0.44) | PTGS1PTGS2FFAR4LMNANR1H2 | |
| SCHEMBL3872156 | 0.86 | FFAR4 (0.45) | FFAR4RUNX1GPR3KIF11 | |
| SCHEMBL178278 | 0.83 | FFAR4 (0.44) | PTGS1PTGS2FFAR4LMNANR1H2 | |
| SCHEMBL23055180 | 0.81 | PDE2A (0.47) | PTGS1PTGS2FFAR4LMNAHRH4 | |
| SCHEMBL14959716 | 0.80 | ADRB2 (0.44) | PTGS1PTGS2FFAR4LMNAHRH4 | |
| SCHEMBL16961512 | 0.80 | GPR3 (0.41) | PTGS1PTGS2FFAR4LMNAHRH4 | |
| SCHEMBL21835675 | 0.80 | FFAR4 (0.41) | FFAR4RUNX1GPR3KIF11 | |
| SCHEMBL16952197 | 0.80 | KDM4E (0.44) | POLB | |
| SCHEMBL16954408 | 0.79 | LMNA (0.39) | PTGS1PTGS2LMNAHRH4NR1H2 | |
| SCHEMBL20526613 | 0.79 | HRH4 (0.43) | PTGS1PTGS2FFAR4LMNAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |