SCHEMBL16958729

SCHEMBL16958729

C=Cc1cccc(CCC)c1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.36
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ALOX5 P09917 1/20 0.35
PTGS2 P35354 1/20 0.35
CA12 O43570 1/20 0.34
CA14 Q9ULX7 1/20 0.34
NFE2L2 Q16236 3/20 0.33
ABCB1 P08183 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
DRD2 P14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27854915 0.90 ALOX5 (0.43) MEN1ALDH1A1GAAKMT2ACA1
SCHEMBL14999526 0.86 CA1 (0.41) MEN1ALDH1A1GAAKMT2ACA1
SCHEMBL16953875 0.85 ELANE (0.37) ALDH1A1GAA
SCHEMBL16960025 0.83 CA1 (0.39) HMGCRCA1CA2ALOX5PTGS2
SCHEMBL10600231 0.81 ALOX5 (0.43) HMGCRALDH1A1CA1CA2ALOX5
SCHEMBL16954578 0.81 CTSS (0.31)
SCHEMBL23020587 0.81 CYP3A4 (0.44) MEN1ALDH1A1GAAKMT2A
SCHEMBL6056491 0.81 ALDH1A1 (0.36) MEN1ALDH1A1GAAKMT2ACA1
SCHEMBL16953029 0.81 CA1 (0.40) MEN1ALDH1A1GAAKMT2ACA1
SCHEMBL809675 0.81 ALDH1A1 (0.36) MEN1ALDH1A1GAAKMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed