Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239105 | 0.79 | TDP1 (0.56) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16958735 | 0.79 | MAPT (0.50) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL19899529 | 0.79 | GPR35 (0.55) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL9913420 | 0.79 | TDP1 (0.56) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16956850 | 0.78 | TSHR (0.36) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16956852 | 0.78 | ESR2 (0.37) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL403033 | 0.76 | SLC18A3 (0.45) | TSHRMAPK1ALDH1A1MAPTMEN1 | |
| SCHEMBL29406926 | 0.76 | ESR2 (0.44) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16961074 | 0.76 | TSHR (0.35) | TSHRMAPK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16957161 | 0.76 | ALDH1A1 (0.33) | TSHRMAPK1CYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |