Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18162312 | 0.95 | MAPT (0.46) | MAPTTSHRHPGDHSD17B10CYP3A4 | |
| SCHEMBL18162316 | 0.86 | POLQ (0.40) | MAPTTSHRHPGDHSD17B10CYP3A4 | |
| SCHEMBL17913158 | 0.86 | ALDH1A1 (0.53) | MAPTTSHRHSD17B10CYP3A4MEN1 | |
| SCHEMBL2946817 | 0.84 | HPGD (0.45) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL18162315 | 0.80 | SIRT6 (0.45) | MAPTTSHRCYP3A4MEN1KMT2A | |
| SCHEMBL12609544 | 0.79 | MAPT (0.51) | MAPTTSHRHPGDHSD17B10CYP3A4 | |
| SCHEMBL12609542 | 0.79 | MAPT (0.51) | MAPTTSHRHPGDHSD17B10CYP3A4 | |
| SCHEMBL239105 | 0.79 | TDP1 (0.56) | MAPTTSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL16958732 | 0.79 | TSHR (0.39) | MAPTTSHRCYP3A4MEN1KMT2A | |
| SCHEMBL9913420 | 0.79 | TDP1 (0.56) | MAPTTSHRCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |