Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.40 |
| ▸ | DRD3 | P35462 | 11/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954813 | 0.80 | EGLN2 (0.37) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL16961551 | 0.76 | EGLN2 (0.37) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL12326822 | 0.76 | HTR2C (0.38) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL1978879 | 0.76 | MEN1 (0.38) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL29672154 | 0.76 | TRPM5 (0.39) | DRD2DRD3EGLN2 | |
| SCHEMBL24690097 | 0.76 | EGLN2 (0.37) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL22082796 | 0.73 | DRD2 (0.41) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL16953765 | 0.72 | EGLN2 (0.35) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL22083034 | 0.72 | EGLN2 (0.35) | DRD2DRD3EGLN2CYP2D6TSHR | |
| SCHEMBL16950372 | 0.72 | EGLN2 (0.35) | DRD2DRD3EGLN2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |