Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962569 | 0.85 | CA1 (0.39) | LMNAL3MBTL1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL16960099 | 0.84 | LMNA (0.36) | LMNAHPGDL3MBTL1MAPTHTT | |
| SCHEMBL16954470 | 0.80 | TLR2 (0.44) | LMNAHPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL16962166 | 0.78 | MEN1 (0.43) | LMNAHPGDL3MBTL1MAPTHTT | |
| SCHEMBL16952378 | 0.78 | L3MBTL1 (0.40) | LMNAHPGDL3MBTL1MAPTHTT | |
| SCHEMBL16956543 | 0.78 | ALDH1A1 (0.40) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL16955812 | 0.77 | F2R (0.34) | LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL16952979 | 0.76 | POLB (0.39) | LMNAHPGDL3MBTL1MAPTHTT | |
| SCHEMBL16955539 | 0.76 | MEN1 (0.35) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL25767325 | 0.76 | SLC6A2 (0.46) | LMNAL3MBTL1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |