Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953287 | 0.85 | MCHR1 (0.34) | LMNAL3MBTL1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL16959656 | 0.84 | LMNA (0.39) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL16961953 | 0.80 | L3MBTL1 (0.38) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9310748 | 0.80 | TLR2 (0.41) | LMNAMAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL16952603 | 0.78 | MEN1 (0.40) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL16951576 | 0.78 | MEN1 (0.33) | LMNAHPGDDRD1MEN1KMT2A | |
| SCHEMBL9310614 | 0.78 | ALDH1A1 (0.40) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL16954898 | 0.78 | L3MBTL1 (0.38) | LMNAHPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL16955538 | 0.78 | KMT2A (0.34) | LMNAHPGDMAPTSMN1; SMN2HTT | |
| SCHEMBL16954090 | 0.77 | F2R (0.32) | KDM4ESLC6A2SLC6A4GAAPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |