Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21313895 | 0.87 | KCNH2 (0.41) | IRAK4SLC6A4KCNH2SLC6A3HTR2A | |
| SCHEMBL16952360 | 0.84 | PTGDR2 (0.38) | SLC6A4KCNH2SLC6A3HTR2APTGDR2 | |
| SCHEMBL7666667 | 0.81 | SLC6A4 (0.49) | SLC6A4KCNH2SLC6A3HTR2APTGDR2 | |
| SCHEMBL16958689 | 0.79 | TRPV4 (0.50) | SLC6A4KCNH2SLC6A3HTR2APTGDR2 | |
| SCHEMBL16950477 | 0.77 | SLC6A9 (0.41) | IRAK4KCNH2PTGDR2EIF4EMKNK1 | |
| SCHEMBL10088433 | 0.76 | AR (0.44) | IRAK4KCNH2EIF4EMKNK1MKNK2 | |
| SCHEMBL21079169 | 0.76 | XDH (0.49) | XDHALDH1A1S1PR1 | |
| SCHEMBL12180330 | 0.76 | FFAR4 (0.48) | ALDH1A1TSHR | |
| SCHEMBL16950480 | 0.76 | IRAK4 (0.37) | IRAK4KCNH2PTGDR2EIF4EMKNK1 | |
| SCHEMBL16959958 | 0.75 | IRAK4 (0.38) | IRAK4KCNH2EIF4EMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |