Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954983 | 0.83 | HPGD (0.33) | SMN1; SMN2NPC1HPGDALDH1A1MRGPRX4 | |
| SCHEMBL16957898 | 0.81 | F2R (0.34) | SMN1; SMN2HPGDALDH1A1GAAMAPT | |
| SCHEMBL16959219 | 0.81 | CTSL (0.35) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL16955031 | 0.81 | ALDH1A1 (0.32) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL16952007 | 0.81 | CYP11B1 (0.38) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16951918 | 0.81 | TSHR (0.48) | ALDH1A1MAPTMEN1KMT2AF2R | |
| SCHEMBL16955693 | 0.79 | P2RX7 (0.37) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL16951096 | 0.79 | TSHR (0.43) | SMN1; SMN2NPC1HPGDALDH1A1MAPT | |
| SCHEMBL16952958 | 0.78 | TSHR (0.34) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL16952565 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |