Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958944 | 0.82 | GABRA1 (0.47) | TUBB1NFE2L2PTGS1PTGS2ALOX5 | |
| SCHEMBL6632434 | 0.78 | TUBB1 (0.46) | TUBB1PTGS1PTGS2ALOX5MAPT | |
| SCHEMBL131635 | 0.78 | NFE2L2 (0.50) | NFE2L2PTGS2MAPTKMT2AALDH1A1 | |
| SCHEMBL29453098 | 0.77 | ALDH1A1 (0.47) | TUBB1HDAC1HDAC6NFE2L2PTGS2 | |
| SCHEMBL6730243 | 0.77 | TUBB1 (0.42) | TUBB1HDAC1HDAC6NFE2L2PTGS1 | |
| SCHEMBL229897 | 0.77 | ALDH1A1 (0.47) | TUBB1HDAC1HDAC6NFE2L2PTGS2 | |
| SCHEMBL13614803 | 0.77 | TP53 (0.45) | TUBB1HDAC1HDAC6NFE2L2PTGS1 | |
| SCHEMBL737915 | 0.77 | KDM4E (0.46) | TUBB1HDAC1HDAC6NFE2L2ACHE | |
| SCHEMBL2164403 | 0.77 | KDM4E (0.46) | TUBB1HDAC1HDAC6NFE2L2ACHE | |
| SCHEMBL10624527 | 0.76 | TUBB1 (0.49) | TUBB1HDAC1HDAC6NFE2L2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |