Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614493 | 0.84 | ALDH1A1 (0.42) | TP53TDP1ALDH1A1TUBB1HDAC8 | |
| SCHEMBL7595327 | 0.82 | TP53 (0.45) | TP53TDP1ALDH1A1TUBB1NFE2L2 | |
| SCHEMBL21094210 | 0.79 | TUBB1 (0.45) | TUBB1NFE2L2HDAC1HDAC6ACHE | |
| SCHEMBL9107503 | 0.79 | CHRNB2 (0.38) | TP53TDP1ALDH1A1TUBB1TRPA1 | |
| SCHEMBL9107888 | 0.79 | CHRNB2 (0.38) | TP53TDP1ALDH1A1TUBB1TRPA1 | |
| SCHEMBL248639 | 0.78 | NFE2L2 (0.50) | TP53TDP1ALDH1A1NFE2L2TRPA1 | |
| SCHEMBL293173 | 0.78 | ALDH1A1 (0.50) | TP53TDP1ALDH1A1TUBB1TRPA1 | |
| SCHEMBL29662132 | 0.78 | NFE2L2 (0.50) | TP53TDP1ALDH1A1NFE2L2TRPA1 | |
| SCHEMBL29407001 | 0.78 | ALDH1A1 (0.50) | TP53TDP1ALDH1A1TUBB1TRPA1 | |
| SCHEMBL6730243 | 0.77 | TUBB1 (0.42) | TUBB1NFE2L2HDAC1HDAC6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661397-B2 | 1,4-disubstituted imidazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-30 | — | — | US | disclosed |
| EP-4112606-A1 | AROMATIC COMPOUND AND USE THEREOF IN PREPARING ANTINEOPLASTIC DRUGS | Shanghai Zheye Biotechnology Co., Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |
| US-20210179634-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | US | disclosed |
| US-20190250510-A1 | PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR | SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-20190250509-A1 | PHOTOSENSITIVE COMPOSITION AND ORGANIC THIN-FILM TRANSISTOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-15 | — | — | US | disclosed |
| US-9828362-B2 | 1,4-disubstituted imidazole derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-11-28 | — | — | US | disclosed |
| US-20170166552-A1 | 1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2017-06-15 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103739440-B | (Z)-2-bromo-1-fluoro-aromatic olefin type compound, as well as synthesis method and use thereof | UNIV TONGJI | 2015-04-08 | — | — | CN | disclosed |
| CN-103739440-A | (Z)-2-bromo-1-fluoro-aromatic olefin type compound, as well as synthesis method and use thereof | UNIV TONGJI | 2014-04-23 | — | — | CN | disclosed |
| EP-2393802-B1 | DIHYDROQUINOLINONE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-08 | — | — | EP | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7306898-B2 | Planographic printing method and planographic printing plate precursor used therein | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7306898-B2 | Planographic printing method and planographic printing plate precursor used therein | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| EP-1566267-B1 | Planographic printing method and planographic printing plate precursor used therein | FUJIFILM CORP (JP) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166552-A1 | 1,4-DISUBSTITUTED IMIDAZOLE DERIVATIVE | NR4A3, NR0B1, NR2C2 | TP53 247/4885TDP1 4690/4885ALDH1A1 278/4885 |
| US-11661397-B2 | 1,4-disubstituted imidazole derivative | NR4A3, NR0B1, NR2C2 | TP53 247/4885TDP1 4690/4885ALDH1A1 278/4885 |
| US-20210179634-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | KDM1B, KDM1A, HDAC1 | TP53 663/4885TDP1 2187/4885ALDH1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.