Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210559 | 0.83 | TRIM24 (0.46) | TRIM24LMNAKAT6ANR1H4SIRT2 | |
| SCHEMBL30266353 | 0.83 | NR1H4 (0.46) | TRIM24KAT6ANR1H4 | |
| SCHEMBL2967940 | 0.81 | TRIM24 (0.55) | TRIM24LMNAKAT6ANR1H4SIRT2 | |
| SCHEMBL694324 | 0.80 | TP53 (0.53) | LMNAMAPTHPGDTSHRMAPK1 | |
| SCHEMBL16953600 | 0.77 | KMT2A (0.50) | KAT6ANR1H4MAPTHPGDTSHR | |
| SCHEMBL6413206 | 0.77 | TRIM24 (0.46) | TRIM24LMNAKAT6ANR1H4SIRT2 | |
| SCHEMBL16954545 | 0.77 | ACACB (0.45) | KAT6AMEN1KMT2A | |
| SCHEMBL16953412 | 0.76 | LTA4H (0.53) | TSHRKMT2A | |
| SCHEMBL16955171 | 0.76 | HPGD (0.42) | MAPTPOLBHPGDXBP1MAOA | |
| SCHEMBL16957855 | 0.76 | MAPK1 (0.43) | LMNAPOLBMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |