Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959875 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11BACE1CYP19A1LMNA | |
| SCHEMBL16957002 | 0.83 | CYP19A1 (0.38) | CYP4F2CYP4A11BACE1CYP19A1LMNA | |
| SCHEMBL16955483 | 0.82 | ABCB11 (0.36) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL16956221 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11BACE1CYP19A1LMNA | |
| SCHEMBL11421086 | 0.81 | LMNA (0.43) | CYP4F2CYP4A11BACE1CYP19A1LMNA | |
| SCHEMBL16954309 | 0.79 | PTGS2 (0.36) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16953048 | 0.79 | GABRA1 (0.34) | KDM4EFABP3FABP4HTT | |
| SCHEMBL16955155 | 0.79 | CYP4F2 (0.44) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16955368 | 0.79 | KMT2A (0.43) | CYP4F2CYP4A11BACE1LMNAKDM4E | |
| SCHEMBL16953471 | 0.79 | LMNA (0.47) | CYP4F2CYP4A11BACE1CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |