Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957584 | 0.88 | LMNA (0.48) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16957457 | 0.80 | ALDH1A1 (0.51) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26686689 | 0.79 | MAPT (0.66) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL2429316 | 0.79 | ALDH1A1 (0.66) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL8973132 | 0.79 | CYP19A1 (0.57) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1136016 | 0.78 | MAPT (0.53) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL8424596 | 0.78 | MAPT (0.60) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL363493 | 0.78 | S1PR4 (0.64) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17572152 | 0.78 | MAPT (0.53) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16961566 | 0.77 | MAPT (0.50) | MAPTNPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |