SCHEMBL8424596

SCHEMBL8424596

CCCOc1ccc(N)cc1[N+](=O)[O-]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
NPC1 O15118 4/20 0.60
RAB9A P51151 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
LMNA P02545 3/20 0.60
RECQL P46063 3/20 0.60
ALDH1A1 P00352 5/20 0.57
MEN1 O00255 2/20 0.57
POLB P06746 2/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
USP2 O75604 1/20 0.57
TP53 P04637 1/20 0.57
GAA P10253 1/20 0.57
CASP1 P29466 1/20 0.57
HTT P42858 1/20 0.57
CASP7 P55210 1/20 0.57
ATM Q13315 1/20 0.57
MAPK1 P28482 2/20 0.52
ALPG P10696 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6402196 0.92 MAPT (0.60) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL28108809 0.91 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11408494 0.90 RECQL (0.58) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11407762 0.89 PRSS1 (0.61) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11407781 0.89 PRSS1 (0.57) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL16775013 0.88 MAPT (0.60) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL4313215 0.87 LMNA (0.58) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11874767 0.86 ALDH1A1 (0.52) MAPTNPC1RAB9ASMN1; SMN2LMNA
Methane SCHEMBL27705473 0.86 LMNA (0.56) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11136715 0.84 PRSS1 (0.54) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866608-A AROMATIC COMPOUNDS BIORESEARCH, INC. (US) 1999-02-02 US claimed
US-5637618-A PHENYL-CONTAINING COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-06-10 US claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL MAPT 2113/4885NPC1 740/4885RAB9A 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.