Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954238 | 0.85 | MAPT (0.42) | PTGDR2CHRNB2CHRNA4KDM4CDRD2 | |
| SCHEMBL16962102 | 0.80 | EPHX2 (0.33) | EPHX2 | |
| SCHEMBL27057381 | 0.79 | CHRNB2 (0.38) | PTGDR2CHRNB2CHRNA4KDM4CDRD2 | |
| SCHEMBL21994522 | 0.79 | CHRNB2 (0.38) | PTGDR2CHRNB2CHRNA4KDM4CDRD2 | |
| SCHEMBL17998791 | 0.79 | CHRNB2 (0.38) | PTGDR2CHRNB2CHRNA4KDM4CDRD2 | |
| SCHEMBL16955092 | 0.77 | SLC6A2 (0.36) | EPHX2DRD2DRD3SLC6A2 | |
| SCHEMBL16955090 | 0.76 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL16956900 | 0.76 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL16956903 | 0.76 | ALDH1A1 (0.31) | EPHX2 | |
| SCHEMBL21386549 | 0.76 | DRD2 (0.32) | PTGDR2DRD2DRD4DRD3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |