Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095492 | 0.83 | KMT2A (0.55) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL30549511 | 0.82 | KMT2A (0.53) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL6312157 | 0.81 | KMT2A (0.44) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL3319361 | 0.76 | KMT2A (0.40) | KMT2ACASP6KEAP1USP30 | |
| SCHEMBL29790479 | 0.74 | KMT2A (0.53) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL22940968 | 0.70 | CASP6 (0.49) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL24359763 | 0.70 | GABRA1 (0.50) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL18378772 | 0.69 | KMT2A (0.47) | KMT2AKEAP1ADRA1DADRA1AADRA1B | |
| SCHEMBL23108234 | 0.69 | ERN1 (0.44) | KMT2ACASP6KEAP1ADRA1DADRA1A | |
| SCHEMBL29767299 | 0.68 | KMT2A (0.55) | KMT2AKEAP1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-A1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-08-05 | — | — | EP | disclosed |