SCHEMBL169650

SCHEMBL169650

Cc1ccc2c(c1)C(=O)C=CC2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
ELANE P08246 1/20 0.52
PIM1 P11309 1/20 0.52
IDO1 P14902 2/20 0.48
CDC25B P30305 2/20 0.48
AKT1 P31749 1/20 0.48
SNCA P37840 1/20 0.48
MAP2K1 Q02750 1/20 0.48
PIN1 Q13526 1/20 0.48
EHMT2 Q96KQ7 1/20 0.48
NSD1 Q96L73 1/20 0.48
EHMT1 Q9H9B1 1/20 0.48
MAPT P10636 2/20 0.45
CDC25A P30304 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13967835 0.81 CA1 (0.45) MAOAMAOBCA1CA2CA4
SCHEMBL11858854 0.81 S100A4 (0.50) MAOAMAOBCA1CA2CA4
SCHEMBL2787339 0.79 CYP2A6 (0.56) MAOAMAOBCA1CA2CA4
SCHEMBL22599583 0.78 CYP2A6 (0.54) MAOAMAOBCA1CA2CA4
SCHEMBL4401141 0.74 ELANE (0.77) MAOAMAOBCA1CA2CA4
SCHEMBL2610165 0.74 ELANE (0.77) MAOAMAOBCA1CA2CA4
SCHEMBL31674914 0.74 ELANE (0.77) MAOAMAOBCA1CA2CA4
SCHEMBL182959 0.74 ELANE (0.86) MAOAMAOBCA1CA2CA4
SCHEMBL583153 0.74 ELANE (0.86) MAOAMAOBCA1CA2CA4
SCHEMBL12108763 0.74 MAOA (0.73) MAOAMAOBCA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN claimed
US-20230150895-A1 SOIL CONDITIONER AND USE THEREOF JAPAN INTERNATIONAL RESEARCH CENTER FOR AGRICULTURAL SCIENCES (JP) 2023-05-18 US claimed
EP-4180502-A1 SOIL CONDITIONER AND USE THEREOF Japan International Research Center for Agricultural Sciences (JP) 2023-05-17 EP claimed
US-20130204019-A1 YIELD-EFFICIENT PROCESS FOR THE PRODUCTION OF HIGHLY PURE 2-METHYL-1, 4-NAPHTHOQUINONE AND ITS DERIVATIVES LONZA LTD. (CH) 2013-08-08 US claimed
US-8350089-B2 Yield-efficient process for the production of highly pure 2-methyl-1,4-naphthoquinone and its derivatives LONZA LTD. (CH) 2013-01-08 US claimed
EP-2523931-A1 YIELD-EFFICIENT PROCESS FOR THE PRODUCTION OF HIGHLY PURE 2-METHYL-1,4-NAPHTHOQUINONE AND ITS DERIVATIVES Lonza Ltd. (CH) 2012-11-21 EP claimed
CN-102666462-A High-yield preparation method of high-purity 2-methyl-1, 4-naphthoquinone and derivatives thereof LONZA AG 2012-09-12 CN claimed
US-20110263904-A1 YIELD-EFFICIENT PROCESS FOR THE PRODUCTION OF HIGHLY PURE 2-METHYL-1,4-NAPHTHOQUINONE AND ITS DERIVATIVES LONZA LTD (CH) 2011-10-27 US claimed
WO-2011085945-A1 YIELD-EFFICIENT PROCESS FOR THE PRODUCTION OF HIGHLY PURE 2-METHYL-1,4-NAPHTHOQUINONE AND ITS DERIVATIVES LONZA LTD (CH) 2011-07-21 WO claimed
EP-2345631-A1 Yield-efficient process for the production of highly pure 2-methyl-1,4-naphthoquinone and its derivatives Lonza Ltd. (CH) 2011-07-20 EP claimed
EP-0848041-B1 Dye precursor from plants of the Medicago genus, its preparation and its use in the manufacture of dyestuffs OREAL (FR) 2001-08-29 EP claimed
US-5989876-A GRINDING; REACTING WITH 1,5-NAPHTHOQUINONE; HAIR DYES L'OREAL (FR) 1999-11-23 US claimed
EP-0848041-A1 Dye precursor from plants of the medicago genus, its preparation and its use in the manufacture of dyestuffs L'OREAL (FR) 1998-06-17 EP claimed
US-5721324-A ADDITION POLYMERIZATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-02-24 US claimed
EP-0430164-B1 Process for preparation of 2-substituted-1,4-naphthoquinone NIPPON CATALYTIC CHEM IND (JP) 1995-03-22 EP claimed
US-5329026-A Oxidation of substituted naphthoquinone, adding a diene compound to reaction product, separation NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1994-07-12 US claimed
US-5241022-A Polyvinyl alcohol with saponification of not less than seventy percent and quinone SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-31 US claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
EP-0430164-A2 Process for preparation of 2-substituted-1,4-naphthoquinone NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1991-06-05 EP claimed
US-4220528-A CONTACTING A GAS WITH A SOLUTION CONTAINING A HYDRAZINE, A QUINONE, AN ALKALI; CONTACTING THE DEOXYGENATED GAS WITH WATER OTSUKA CHEMICAL CO., LTD. (JP) 1980-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150895-A1 SOIL CONDITIONER AND USE THEREOF H1-0, ARG1, H1-2 MAOA 1391/4885MAOB 2074/4885CA1 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.