SCHEMBL2787339

SCHEMBL2787339

Cc1ccc2cc3c(cc2c1)C(=O)C=CC3=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.56
CYP1A2 P05177 3/20 0.56
TDP1 Q9NUW8 2/20 0.48
CA9 Q16790 3/20 0.42
CA12 O43570 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PIM1 P11309 1/20 0.42
KDM4E B2RXH2 1/20 0.41
APAF1 O14727 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
MCL1 Q07820 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAOB P27338 6/20 0.41
ADORA3 P0DMS8 1/20 0.41
S100A4 P26447 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22599583 0.98 CYP2A6 (0.54) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL169650 0.79 MAOA (0.54) TDP1CA9PIM1KDM4EAPAF1
SCHEMBL22599584 0.77 CYP2A6 (0.64) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL6888140 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL29837229 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL6056946 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL4368477 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL2463834 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL2490023 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12
SCHEMBL31612403 0.75 CYP1A2 (0.87) CYP2A6CYP1A2TDP1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020215388-A1 DEEP RED LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, PREPARATION METHOD THEREFOR, AND ELECTROLUMINESCENT DEVICE 武汉华星光电半导体显示技术有限公司 2020-10-29 WO disclosed
US-8394512-B2 Phosphaphenanthrene compounds and organic light emitting diode using the same INKTEC CO., LTD. (KR) 2013-03-12 US disclosed
US-20100252818-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME INKTEC CO., LTD. (KR) 2010-10-07 US disclosed
US-7799776-B2 Indoleamine 2,3-dioxygenase (IDO) inhibitors THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2010-09-21 US disclosed
US-7799776-B2 Indoleamine 2,3-dioxygenase (IDO) inhibitors THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2010-09-21 US disclosed
EP-2134808-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME Inktec Co., Ltd. (KR) 2009-12-23 EP disclosed
EP-2130826-A1 Annulins A, B, C or analogs as indoleamine 2,3-dioxygenase (IDO) inhibitors for treatment of cancer The University of British Columbia (CA) 2009-12-09 EP disclosed
US-20090042868-A1 Indoleamine 2,3-Dioxygenase (IDO) Inhibitors THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2009-02-12 US disclosed
US-20090042868-A1 Indoleamine 2,3-Dioxygenase (IDO) Inhibitors THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2009-02-12 US disclosed
WO-2008123722-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME INKTEC CO., LTD. (KR) 2008-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100252818-A1 PHOSPHAPHENANTHRENE COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME DDT, PPOX, ODC1 CYP2A6 760/4885CYP1A2 419/4885TDP1 2028/4885
US-20090042868-A1 Indoleamine 2,3-Dioxygenase (IDO) Inhibitors IDO1, IDO2, TDO2 CYP2A6 576/4885CYP1A2 363/4885TDP1 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.