SCHEMBL16965115

SCHEMBL16965115

CN(C)C(=O)Oc1ccccc1OC(=O)N(C)C

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.60
NCEH1 Q6PIU2 10/20 0.59
TSHR P16473 2/20 0.59
PKM P14618 2/20 0.59
NPC1 O15118 1/20 0.59
BCHE P06276 1/20 0.56
LMNA P02545 1/20 0.56
ALDH1A1 P00352 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14467975 0.92 NCEH1 (0.53) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL29728586 0.89 NCEH1 (0.54) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL16965297 0.89 NCEH1 (0.54) RAB9ANCEH1TSHRPKMNPC1
O-Tolyl Dimethylcarbamate SCHEMBL8927621 0.87 NCEH1 (0.56) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL10574854 0.87 ALDH1A1 (0.65) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL11299389 0.87 L3MBTL1 (0.56) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL8927620 0.86 NCEH1 (0.51) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL31522635 0.86 NCEH1 (0.51) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL28540620 0.86 MAOA (0.56) RAB9ANCEH1TSHRPKMNPC1
SCHEMBL28007495 0.86 NCEH1 (0.58) RAB9ANCEH1TSHRPKMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286504-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-04-29 US disclosed
EP-4031588-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-09-20 EP disclosed
US-20220298272-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-09-22 US disclosed
EP-4031588-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2022-07-27 EP disclosed
WO-2021052733-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-03-25 WO disclosed
EP-2900706-B1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENTS OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA SRL (IT) 2016-12-14 EP disclosed
US-20150266981-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENT OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-09-24 US disclosed
EP-2900706-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENTS OBTAINED THEREFROM Basell Poliolefine Italia S.r.l. (IT) 2015-08-05 EP disclosed