SCHEMBL1696779

SCHEMBL1696779

O=c1ccn([C@@H]2O[C@H](C(O)Cl)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.61
SLC28A2 O43868 1/20 0.61
SLC29A1 Q99808 1/20 0.61
SLC28A3 Q9HAS3 1/20 0.61
P2RY2 P41231 10/20 0.54
P2RY6 Q15077 8/20 0.51
P2RY4 P51582 3/20 0.50
P2RY14 Q15391 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846581 0.90 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4950152 0.89 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4280246 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL123664 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21275617 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23710653 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1585708 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL566228 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16629728 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL800228 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020177695-A1 Nucleic acid probes and methods DUKE UNIVERSITY 2002-11-28 US claimed
US-6288221-B1 REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES DUKE UNIVERSITY 2001-09-11 US claimed
CN-119569869-A SLC15A4 activated antibody and application thereof 北京理工大学 2025-03-07 CN disclosed
US-10456463-B2 Vaccines comprising cholesterol and CpG as sole adjuvant-carrier molecules Zoetis Belgium S.A (BE) 2019-10-29 US disclosed
EP-2575878-B1 VACCINES COMPRISING CHOLESTEROL AND CPG AS SOLE ADJUVANT-CARRIER MOLECULES ZOETIS BELGIUM S A (BE) 2018-06-13 EP disclosed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP disclosed
WO-2015196128-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO disclosed
EP-2575878-A1 VACCINES COMPRISING CHOLESTEROL AND CPG AS SOLE ADJUVANT - CARRIER MOLECULES Pfizer Animal Health S.A. (BE) 2013-04-10 EP disclosed
US-20130084306-A1 VACCINES COMPRISING CHOLESTEROL AND CPG AS SOLE ADJUVANT-CARRIER MOLECULES COLEY PHARMACEUTICAL GROUP INC. (US) 2013-04-04 US disclosed
US-8252768-B2 Designer therapy of pancreatic tumors UNIVERSITY OF MIAMI (US) 2012-08-28 US disclosed
WO-2011148356-A1 VACCINES COMPRISING CHOLESTEROL AND CPG AS SOLE ADJUVANT - CARRIER MOLECULES COLEY PHARMACEUTICAL GROUP, INC. (US) 2011-12-01 WO disclosed
US-20090325897-A1 DESIGNER THERAPY OF PANCREATIC TUMORS UNIVERSITY OF MIAMI (US) 2009-12-31 US disclosed
WO-2008085611-A2 DESIGNER THERAPHY OF PANCREATIC TUMORS UNIVERSITY OF MIAMI (US) 2008-07-17 WO disclosed
US-20030219805-A1 Detection of alternative and aberrant mRNA splicing UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE 2003-11-27 US disclosed
US-20020177695-A1 Nucleic acid probes and methods DUKE UNIVERSITY 2002-11-28 US disclosed
US-6288221-B1 REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES DUKE UNIVERSITY 2001-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020177695-A1 Nucleic acid probes and methods NUDT1, NT5C3B, NT5C2 SLC28A1 152/4885SLC28A2 162/4885SLC29A1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.