SCHEMBL4950152

SCHEMBL4950152

NC(O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.61
SLC28A2 O43868 1/20 0.61
SLC29A1 Q99808 1/20 0.61
SLC28A3 Q9HAS3 1/20 0.61
P2RY2 P41231 9/20 0.54
P2RY6 Q15077 7/20 0.51
P2RY4 P51582 3/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
P2RY14 Q15391 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846581 0.90 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL10782234 0.89 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1696779 0.89 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4390141 0.88 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4390144 0.88 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23710653 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1585708 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL566228 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL123664 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21275617 0.88 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN disclosed
US-7442788-B2 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-10-28 US disclosed
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-08-28 US disclosed
EP-1295892-A1 ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME Japan Science and Technology Corporation (JP) 2003-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same RNGTT, RNMT, UPF1 SLC28A1 110/4885SLC28A2 60/4885SLC29A1 347/4885
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 SLC28A1 317/4885SLC28A2 259/4885SLC29A1 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.