SCHEMBL1697197

SCHEMBL1697197

Oc1ccccc1-c1cccc(-c2ccccc2O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
HPGD P15428 4/20 0.55
HSD17B10 Q99714 4/20 0.55
BCL2L1 Q07817 1/20 0.55
F7 P08709 1/20 0.53
LMNA P02545 3/20 0.53
ALOX15 P16050 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
EGFR P00533 2/20 0.53
CA2 P00918 2/20 0.53
FYN P06241 2/20 0.53
MMP9 P14780 2/20 0.53
RECQL P46063 2/20 0.53
ADAMTS4 O75173 1/20 0.53
CA1 P00915 1/20 0.53
MMP2 P08253 1/20 0.53
MMP8 P22894 1/20 0.53
CA6 P23280 1/20 0.53
CDK2 P24941 1/20 0.53
MMP12 P39900 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79393 0.92 HPGD (0.58) ALDH1A1HPGDHSD17B10BCL2L1F7
SCHEMBL13992463 0.89 HPGD (0.55) ALDH1A1HPGDHSD17B10BCL2L1F7
SCHEMBL8778334 0.88 HPGD (0.70) ALDH1A1HPGDHSD17B10BCL2L1F7
SCHEMBL28574 0.87 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1LMNA
SCHEMBL29623192 0.87 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1LMNA
SCHEMBL30442890 0.87 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1LMNA
SCHEMBL7845497 0.84 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1LMNA
Catechol SCHEMBL21408977 0.84 ALDH1A1 (0.71) ALDH1A1HPGDHSD17B10BCL2L1LMNA
Hydrogen Sulfide SCHEMBL20536042 0.84 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1LMNA
SCHEMBL477382 0.84 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7696297-B2 Branched polycarbonates and processes for producing the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-04-13 US claimed
US-20090326183-A1 BRANCHED POLYCARBONATE-POLYSILOXANE COPOLYMERS AND PROCESSES FOR PRODUCING THE SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-31 US claimed
US-20090326149-A1 BRANCHED POLYCARBONATES AND PROCESSES FOR PRODUCING THE SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-31 US claimed
JP-61069769-A None JP disclosed
EP-3152770-B1 FOAMED POLYCARBONATE SEPARATORS AND CABLES THEREOF GEN CABLE TECHNOLOGIES CORP (US) 2020-03-25 EP disclosed
US-20190152998-A1 SYNTHESIS OF m-TERPHENYL PENDANT BIS-ETHER LIGANDS AND METAL COMPLEX AND THEIR USE IN OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-23 US disclosed
EP-2855575-B1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-03-07 EP disclosed
EP-3152770-A1 FOAMED POLYCARBONATE SEPARATORS AND CABLES THEREOF General Cable Technologies Corporation (US) 2017-04-12 EP disclosed
US-20150357095-A1 FOAMED POLYCARBONATE SEPARATORS AND CABLES THEREOF GENERAL CABLE TECHNOLOGIES CORPORATION 2015-12-10 US disclosed
EP-2855575-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC Innovative Plastics IP B.V. (NL) 2015-04-08 EP disclosed
EP-2576214-B1 A MULTILAYER SHEET AND METHODS OF MAKING AND ARTICLES COMPRISING THE MULTILAYER SHEET SABIC INNOVATIVE PLASTICS IP (NL) 2014-12-24 EP disclosed
WO-2011148330-A1 A MULTILAYER SHEET AND METHODS OF MAKING AND ARTICLES COMPRISING THE MULTILAYER SHEET SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-01 WO disclosed
US-7696297-B2 Branched polycarbonates and processes for producing the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-04-13 US disclosed
US-20090326183-A1 BRANCHED POLYCARBONATE-POLYSILOXANE COPOLYMERS AND PROCESSES FOR PRODUCING THE SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-31 US disclosed
US-20090326149-A1 BRANCHED POLYCARBONATES AND PROCESSES FOR PRODUCING THE SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-31 US disclosed
US-5206334-A Improved blow molding characteristics GENERAL ELECTRIC COMPANY (US) 1993-04-27 US disclosed
US-5105025-A 2',4,4\"-m-terphenyltriols and fungal strain used to make same GENERAL ELECTRIC COMPANY (US) 1992-04-14 US disclosed
US-5049498-A Fungal strain used to make 2',4,4\"-m-terphenyltriols GENERAL ELECTRIC COMPANY (US) 1991-09-17 US disclosed
US-5049496-A Method for microbiologically hydroxylating biphenyl and terphenyl compounds GENERAL ELECTRIC COMPANY (US) 1991-09-17 US disclosed
JP-S6169769-A NOVEL POLYEPOXIDE COMPOUND AND ITS PREPARATION MITSUI PETROCHEM IND LTD 1986-04-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152998-A1 SYNTHESIS OF m-TERPHENYL PENDANT BIS-ETHER LIGANDS AND METAL COMPLEX AND THEIR USE IN OLEFIN POLYMERIZATION OPRM1, TERF2, OSTC ALDH1A1 2450/4885HPGD 2868/4885HSD17B10 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.