Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 2/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537414 | 1.00 | SLC7A5 (0.50) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Tyrosine SCHEMBL8392469 | 0.95 | SLC7A5 (0.60) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Glutamine SCHEMBL8134265 | 0.92 | ALOX15 (0.47) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| SCHEMBL6046921 | 0.90 | SLC7A5 (0.51) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| SCHEMBL9346887 | 0.90 | SLC7A5 (0.51) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Lysine SCHEMBL5358311 | 0.87 | ITGB3 (0.52) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Lysine SCHEMBL4610451 | 0.87 | ITGB3 (0.52) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| SCHEMBL6519873 | 0.86 | SLC7A5 (0.53) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Asparagine SCHEMBL7758514 | 0.84 | SLC7A5 (0.51) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| Cysteine SCHEMBL29288515 | 0.84 | PTPN1 (0.46) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102611-A1 | HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF | Cangene Corporation (CA) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015113169-A1 | HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF | CNJ HOLDINGS, INC. (CA) | 2015-08-06 | — | — | WO | disclosed |