Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742875 | 1.00 | ALDH1A1 (0.41) | ALDH1A1RNPEPTSHRCTSSCTSK | |
| SCHEMBL11053310 | 0.86 | RNPEP (0.39) | ALDH1A1RNPEPTSHRCTSSCTSK | |
| SCHEMBL11053305 | 0.86 | RNPEP (0.39) | ALDH1A1RNPEPTSHRCTSSCTSK | |
| SCHEMBL9114022 | 0.82 | CTSB (0.50) | ALDH1A1CTSSCTSKCTSBFOLH1 | |
| SCHEMBL8722926 | 0.81 | ALDH1A1 (0.38) | ALDH1A1RNPEP | |
| SCHEMBL3923432 | 0.81 | CTSB (0.49) | ALDH1A1CTSSCTSKCTSBFOLH1 | |
| SCHEMBL3911006 | 0.78 | — | — | |
| SCHEMBL56437 | 0.78 | HDAC7 (0.35) | ALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL3911009 | 0.78 | — | — | |
| SCHEMBL3819093 | 0.76 | CTSK (0.56) | ALDH1A1TSHRCTSSCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1271049-C | Method for synthesizing polycarbo amide | SHANGHAI MEDICINES INST CHINES (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-1470506-A | Method for synthesizing polycarbo amide | 中国科学院上海药物研究所 | 2004-01-28 | — | — | CN | claimed |
| US-5236950-A | Phytol and isophytol derivatives | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| CN-111825611-A | 4(1H) -quinovone derivatives and uses thereof | 中央研究院 | 2020-10-27 | — | — | CN | disclosed |
| US-10414737-B2 | Process methods for phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| US-20190031626-A1 | PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2019-01-31 | — | — | US | disclosed |
| EP-2177522-B1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU PHARMA CO LTD (CN) | 2013-09-04 | — | — | EP | disclosed |
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LTD. (IN) | 2013-05-16 | — | — | US | disclosed |
| US-8318716-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-11-27 | — | — | US | disclosed |
| US-8293895-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-10-23 | — | — | US | disclosed |
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| EP-2177522-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP Biosciences Co., Ltd. (CN) | 2010-04-21 | — | — | EP | disclosed |
| WO-2007115685-A1 | METHOD FOR PRODUCING BIPHENYLAMINES FROM VINYL ANILINES | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| CN-1267435-C | Novel process for preparing oxabispidines | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | CN | disclosed |
| CN-1196696-C | New thiochromane derivatives and use as thrombin inhibitors | ASTRAZENECA AG (SE) | 2005-04-13 | — | — | CN | disclosed |
| CN-1520417-A | New process for prepn. of oxabispidines | — | 2004-08-11 | — | — | CN | disclosed |
| CN-1441799-A | New thiochromane derivatives and use as thrombin inhibitors | ASTRAZENECA AG (SE) | 2003-09-10 | — | — | CN | disclosed |
| EP-0927019-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998048768-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0326067-A2 | Use of cyclophilin as an anti-inflammatory and immunomodulatory agent | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | MYT1, TET1, LPXN | ALDH1A1 2151/4885RNPEP 233/4885TSHR 3350/4885 |
| US-10414737-B2 | Process methods for phosphatidylinositol 3-kinase inhibitors | PIK3CB, PIK3CA, PIP4K2B | ALDH1A1 3592/4885RNPEP 3036/4885TSHR 4097/4885 |
| US-20190031626-A1 | PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CB, PIK3CA, PIP4K2B | ALDH1A1 3592/4885RNPEP 3036/4885TSHR 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.