Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 9/20 | 0.43 |
| ▸ | CTSD | P07339 | 8/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923432 | 0.99 | CTSB (0.49) | CTSBALDH1A1BACE1CTSDFOLH1 | |
| SCHEMBL3834367 | 0.84 | ALDH1A1 (0.55) | CTSBALDH1A1CTSKCTSS | |
| SCHEMBL3365403 | 0.84 | ALDH1A1 (0.55) | CTSBALDH1A1CTSKCTSS | |
| SCHEMBL1697385 | 0.82 | ALDH1A1 (0.41) | CTSBALDH1A1FOLH1CTSKCTSS | |
| SCHEMBL742875 | 0.82 | ALDH1A1 (0.41) | CTSBALDH1A1FOLH1CTSKCTSS | |
| SCHEMBL21012039 | 0.81 | CTSD (0.50) | CTSBALDH1A1BACE1CTSDFOLH1 | |
| SCHEMBL20255738 | 0.81 | CTSD (0.50) | CTSBALDH1A1BACE1CTSDFOLH1 | |
| SCHEMBL15539031 | 0.81 | CTSS (0.49) | ALDH1A1BACE1CTSKCTSS | |
| SCHEMBL21049237 | 0.80 | ALDH1A1 (0.60) | CTSBALDH1A1BACE1CTSDFOLH1 | |
| SCHEMBL21049238 | 0.80 | ALDH1A1 (0.60) | CTSBALDH1A1BACE1CTSDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668770-A4 | — | — | 1995-09-27 | — | — | EP | disclosed |
| EP-0668770-A1 | $g(a)-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |