Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.38 |
| ▸ | NQO2 | P16083 | 8/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732883 | 0.79 | MAPT (0.35) | SLC6A2OPRM1SIGMAR1MTNR1B | |
| SCHEMBL7943657 | 0.74 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL7951233 | 0.73 | HTR2B (0.50) | ADRB2HTR1AADRA2AADRA2BSLC6A2 | |
| SCHEMBL18241632 | 0.72 | MTNR1A (0.38) | ADRB2HTR1AADRA2AADRA2BSLC6A2 | |
| SCHEMBL28415469 | 0.71 | HTR2C (0.43) | ADRB2HTR1AADRA2AADRA2BSLC6A2 | |
| SCHEMBL2351032 | 0.68 | FFAR1 (0.47) | SLC6A2SLC6A3 | |
| SCHEMBL5480835 | 0.68 | CYP24A1 (0.46) | SIGMAR1MTNR1AMTNR1BNQO2PTGDR2 | |
| SCHEMBL19490670 | 0.67 | SLC6A2 (0.43) | ADRB2HTR1AADRA2AADRA2BSLC6A2 | |
| SCHEMBL3411463 | 0.65 | OPRM1 (0.38) | OPRM1OPRK1MTNR1AMTNR1BNQO2 | |
| SCHEMBL2347895 | 0.65 | F2RL1 (0.42) | SLC6A2SLC6A3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099671-B1 | METHOD FOR THE PRODUCTION OF 1-INDANOLES AND 1-INDANAMINES | BAYER CROPSCIENCE AG (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-3099671-A1 | METHOD FOR PRODUCING 1-INDANOLES AND 1-INDANAMINES | Bayer CropScience Aktiengesellschaft (DE) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015113903-A1 | METHOD FOR PRODUCING 1-INDANOLES AND 1-INDANAMINES | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | WO | disclosed |