Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974091 | 0.79 | ADRB2 (0.43) | SLC6A2SIGMAR1OPRM1MTNR1B | |
| SCHEMBL12745141 | 0.75 | SLC6A2 (0.40) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL19852061 | 0.70 | ALDH1A1 (0.40) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL12416516 | 0.69 | SLC6A2 (0.38) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL18241637 | 0.68 | MAPT (0.38) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL14429883 | 0.66 | ALOX15 (0.44) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL1745011 | 0.66 | ALOX15 (0.44) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL700442 | 0.66 | SIGMAR1 (0.40) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL9493694 | 0.65 | EGFR (0.37) | MAPTALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL28424107 | 0.64 | SLC6A2 (0.46) | MAPTALDH1A1TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099671-B1 | METHOD FOR THE PRODUCTION OF 1-INDANOLES AND 1-INDANAMINES | BAYER CROPSCIENCE AG (DE) | 2017-12-27 | — | — | EP | disclosed |