Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3327687 | 0.93 | ALDH1A1 (0.48) | ALDH1A1DDAH1TSHRHPGDTDP1 | |
| SCHEMBL14667675 | 0.89 | ALDH1A1 (0.47) | ALDH1A1DDAH1TSHRGPR84FFAR1 | |
| SCHEMBL16411854 | 0.86 | ALDH1A1 (0.48) | ALDH1A1DDAH1TSHRGPR84FFAR1 | |
| SCHEMBL2634911 | 0.82 | ALDH1A1 (0.41) | ALDH1A1DDAH1TSHRHPGDTDP1 | |
| SCHEMBL12972386 | 0.82 | LTA4H (0.50) | ALDH1A1TBXAS1 | |
| SCHEMBL3124110 | 0.82 | GPR84 (0.57) | ALDH1A1DDAH1TSHRGPR84FFAR1 | |
| SCHEMBL28065252 | 0.82 | LTA4H (0.50) | ALDH1A1TBXAS1 | |
| SCHEMBL14628724 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TBXAS1 | |
| SCHEMBL18641836 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TBXAS1 | |
| SCHEMBL8469936 | 0.80 | RNPEP (0.55) | ALDH1A1DDAH1TSHRGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555008-B2 | Synthesis of hyperbranched amphiphilic polyester and theranostic nanoparticles thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-9555008-B2 | Synthesis of hyperbranched amphiphilic polyester and theranostic nanoparticles thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160256402-A1 | SYNTHESIS OF HYPERBRANCHED AMPHIPHILIC POLYESTER AND THERANOSTIC NANOPARTICLES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-09-08 | — | — | US | disclosed |
| US-9267002-B2 | Synthesis of hyperbranched amphiphilic polyester and theranostic nanoparticles thereof | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-9095611-B1 | Synthesis of hyperbranched amphiphilic polyester and theranostic nanoparticles thereof | THE UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256402-A1 | SYNTHESIS OF HYPERBRANCHED AMPHIPHILIC POLYESTER AND THERANOSTIC NANOPARTICLES THEREOF | LIPA, DLST, ANXA6 | ALDH1A1 2409/4885DDAH1 107/4885TSHR 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.