SCHEMBL16977656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3437309	0.93	THRB (0.47)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL3437321	0.92	THRB (0.48)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL3437306	0.90	CA12 (0.51)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL22099126	0.90	THRB (0.37)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL22099229	0.89	THRB (0.38)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL3437320	0.89	CA12 (0.52)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL13904883	0.89	THRB (0.54)	THRBAKR1B10AKR1B1KMT2APPARA
	SCHEMBL13904899	0.88	HTT (0.43)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL22219380	0.87	CA12 (0.46)	THRBALDH1A1CYP3A4TSHRLMNA
	SCHEMBL16606333	0.87	THRB (0.54)	THRBALDH1A1CYP3A4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.