Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9885435 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL18867335 | 0.75 | MAOA (0.44) | TSHRCTSKMEN1KMT2A | |
| SCHEMBL19576058 | 0.74 | ALOX15 (0.36) | SMN1; SMN2CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL22341245 | 0.73 | PSMB5 (0.39) | — | |
| SCHEMBL31120959 | 0.72 | KDM4E (0.36) | SMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL5553307 | 0.72 | LMNA (0.48) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL20997122 | 0.72 | ALOX15 (0.35) | SMN1; SMN2CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL606445 | 0.72 | — | — | |
| SCHEMBL25963168 | 0.71 | SMN1; SMN2 (0.31) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL25130121 | 0.71 | KDM4E (0.34) | SMN1; SMN2TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015115091-A1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | 第一三共株式会社 | 2015-08-06 | — | — | WO | disclosed |