Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438655 | 0.69 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9368962 | 0.66 | FAAH (0.45) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28070758 | 0.64 | ALDH1A1 (0.37) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9427893 | 0.62 | — | — | |
| SCHEMBL26822942 | 0.62 | ATM (0.42) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7268279 | 0.61 | ALDH1A1 (0.43) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9594434 | 0.61 | ALDH1A1 (0.38) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28065581 | 0.61 | — | — | |
| SCHEMBL10539145 | 0.61 | RAB9A (0.38) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL425384 | 0.59 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517274-B2 | Glycoconjugation processes and compositions | PFIZER INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20150216996-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | PFIZER INC. | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216996-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | GNE, SIGLEC7, SIGLEC9 | LMNA 4197/4885MEN1 4050/4885KMT2A 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.