SCHEMBL16985243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18233460	0.82	CA2 (0.51)	CA2CA12CA1CA9CCR2
	SCHEMBL18223712	0.82	CA2 (0.51)	CA2CA12CA1CA9ATM
	SCHEMBL18223609	0.78	TRPA1 (0.45)	CA2CA12CA1CA9CCR2
	SCHEMBL6683885	0.76	CYP2A6 (0.46)	CA2CCR2CHRM2CHRM4CHRM5
	SCHEMBL16985241	0.76	CA2 (0.67)	CA2CA12CA1CA9CCR2
	SCHEMBL18233477	0.73	TRPA1 (0.50)	CA2CA12CA1CA9CCR2
	SCHEMBL18233472	0.73	ATM (0.42)	CA2CA12CA1CA9ATM
	SCHEMBL20577822	0.73	TRPA1 (0.50)	CA2CA12CA1CA9CCR2
	SCHEMBL18233473	0.72	CA2 (0.39)	CA2CA12CA1CA9ATM
	SCHEMBL18233471	0.72	CA2 (0.42)	CA2CA12CA1CA9ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.