SCHEMBL16985270

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16985293	0.92	POLB (0.38)	PKMPOLBL3MBTL1CYP2C9MEN1
	SCHEMBL19716115	0.90	POLB (0.39)	PKMPOLBL3MBTL1LMNACYP2C9
	SCHEMBL19716126	0.90	POLB (0.39)	PKMPOLBL3MBTL1LMNACYP2C9
	SCHEMBL23275100	0.87	PKM (0.40)	PKMPOLBL3MBTL1LMNACYP2C9
	SCHEMBL16985300	0.83	PKM (0.36)	PKMPOLBLMNACYP2C9MEN1
	SCHEMBL26121604	0.81	PKM (0.38)	PKMPOLBL3MBTL1LMNAMEN1
	SCHEMBL20555241	0.81	PKM (0.41)	PKMPOLBL3MBTL1LMNACYP2C9
	SCHEMBL16985367	0.81	PKM (0.34)	PKMPOLBL3MBTL1LMNAMEN1
	SCHEMBL16985297	0.80	PKM (0.35)	PKMPOLBL3MBTL1LMNACYP2C9
	SCHEMBL17610463	0.78	L3MBTL1 (0.40)	POLBL3MBTL1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.