Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271182 | 0.85 | POLB (0.52) | ALDH3A1HCAR3POLBMCOLN3ALDH1A1 | |
| SCHEMBL3991397 | 0.82 | POLB (0.62) | HCAR3POLBMCOLN3ALDH1A1MAPT | |
| SCHEMBL9588620 | 0.81 | POLB (0.57) | POLBMCOLN3ALDH1A1MAPTMAPK1 | |
| SCHEMBL11035135 | 0.79 | POLB (0.47) | ALDH3A1HCAR3POLBMCOLN3ALDH1A1 | |
| SCHEMBL1524806 | 0.79 | ALDH3A1 (0.65) | ALDH3A1HCAR3POLBALDH1A1MAPT | |
| SCHEMBL28718121 | 0.78 | ALDH3A1 (0.63) | ALDH3A1HCAR3POLBALDH1A1MAPT | |
| SCHEMBL17309819 | 0.78 | ALDH3A1 (0.63) | ALDH3A1HCAR3POLBALDH1A1MAPT | |
| SCHEMBL30383757 | 0.77 | SMN1; SMN2 (0.44) | ALDH3A1HCAR3POLBMCOLN3ALDH1A1 | |
| SCHEMBL3823448 | 0.77 | ALDH1A1 (0.54) | POLBMCOLN3ALDH1A1MAPTMAPK1 | |
| SCHEMBL29833050 | 0.77 | POLB (0.53) | HCAR3POLBMCOLN3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | ALPG, XDH, HEXD | ALDH3A1 283/4885HCAR3 1080/4885POLB 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.